Increase of intra-occular pressure especially in patients with closed-angle glaucoma. Dryness of the mouth with difficulty in swallowing and talking, thirst, reduced bronchial secretions, dilatation of the pupils (mydriasis) with loss of accommodation (cycloplegia) and photophobia, flushing and dryness of the skin, transient bradycardia followed by tachycardia, with palpitations and arrhythmias, and difficulty in micturation, as well as reduction in the tone and motility of gastro-intestinal tract leading to constipation, elevated body temperature and CNS excitation that is caused by the antimuscarinic effect. Occasionally vomiting may also occur.
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